BD APC Mouse Anti-Human CD105(266) 货号562408

促销价：

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品牌：

CAS号：

计量单位：

支

货号：

562408

生产日期：

有效日期：

2023-05-31

是否临期：

临期产品

库存数量:

1(支)

购买数量：

湖南晶科生物科技有限公司

企业类型：私营企业

注册资金：301万元

注册年份： 2009-12-11

主营：生物制品研发;化学试剂和助剂(监控化学品、危险化学品除外)、化工原料、教学仪器、玻璃仪器、通用仪器仪表、生物试剂、化学试剂及日用化学产品(不含危险及监控化学品)、医疗实验室设备和器具、医学教学仪器、电子计算机、机电产品、计算机软件、办公设备耗材、实验室耗材、安全技术防范产品销售，自然科学研究和试验发展，电子产品的零售;软件开发，计算机技术开发、技术服务:生物技术咨询、交流服务;信息系统集成服务，医学检验技术服务;计算机、办公设备和专用设备维修。((依法须经批准的项目，经相关部门批准后方可开展经营活动，未经批准不得从事P2P网贷、股权众筹、互联网保险、资管及跨界从事金融、第三方支付、虚拟货币交易、ICO、非法外汇等互联网金融业务)

地址：湖南省-长沙市

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产品详情

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耦联标记

APC

抗原名称

CD105

宿主

Mouse BALB/c IgG1, κ

免疫原

Human Umbilical Vein Endothelial Cells

简单描述

The 266 monoclonal antibody specifically binds to CD105. CD105 is a type I transmembrane glycoprotein that is encoded by END (Endoglin) and belongs to the transforming growth factor-β (TGF-β) type III receptor family. CD105 is expressed on cells as a homodimer comprised of ~95 kDa subunits. CD105 is expressed on vascular endothelial cells and placental syncytiotrophoblasts and at lower levels on stromal fibroblasts. It is also expressed on mesenchymal stem cells, erythroid precursors, activated macrophages, pre-B cells, and some tumor cells and cell lines including U937 cells. CD105 serves as a regulatory component of the TGF-β receptor system. In association with TGF- βRI or TGF- βRII, CD105 binds TGF-β1 and TGF-β3 with high affinity but does not bind to TGF-β2. Expression of CD105 is increased on activated endothelium in tissues undergoing angiogenesis, such as in tumors, or in cases of wound healing or dermal inflammation.

商品描述

The 266 monoclonal antibody specifically binds to CD105. CD105 is a type I transmembrane glycoprotein that is encoded by END (Endoglin) and belongs to the transforming growth factor-β (TGF-β) type III receptor family. CD105 is expressed on cells as a homodimer comprised of ~95 kDa subunits. CD105 is expressed on vascular endothelial cells and placental syncytiotrophoblasts and at lower levels on stromal fibroblasts. It is also expressed on mesenchymal stem cells, erythroid precursors, activated macrophages, pre-B cells, and some tumor cells and cell lines including U937 cells. CD105 serves as a regulatory component of the TGF-β receptor system. In association with TGF- βRI or TGF- βRII, CD105 binds TGF-β1 and TGF-β3 with high affinity but does not bind to TGF-β2. Expression of CD105 is increased on activated endothelium in tissues undergoing angiogenesis, such as in tumors, or in cases of wound healing or dermal inflammation.

同种型

Mouse BALB/c IgG1, κ

克隆号

266

产品详情

APC
Allophycocyanin (APC), is part of the BD family of phycobiliprotein dyes. This fluorochrome is a multimeric fluorescent phycobiliprotein with excitation maximum (Ex Max) of 651 nm and an emission maximum (Em Max) at 660 nm. APC is designed to be excited by the Red (627-640 nm) laser and detected using an optical filter centered near 660 nm (e.g., a 660/20 nm bandpass filter). Please ensure that your instrument’s configurations (lasers and optical filters) are appropriate for this dye.
格式:APC
激发源:Red 627-640 nm
最多激发源:651 nm
最多发射源:660 nm

应用

实验应用

Flow cytometry (Routinely Tested)

推荐用量

5 µl

反应种属

Human (QC Testing)

背景

别名

END; Endoglin; HHT1; MSC; ORW; ORW1

制备和贮存

存储溶液

Aqueous buffered solution containing BSA and ≤0.09% sodium azide.

保存方式

Aqueous buffered solution containing BSA and ≤0.09% sodium azide.